Sick sinus syndrome aggravated by carbamazepine therapy for epilepsy.
نویسندگان
چکیده
A case of sick sinus syndrome aggravated by carbamazepine prescribed for epilepsy is described. A 70 year old woman with previously stable psychomotor epilepsy experienced syncope of increased frequency after her anticonvulsant was changed to carbamazepine. ECG monitoring confirmed a severe sick sinus syndrome which improved on carbamazepine withdrawal. Failure to distinguish carbamazepine-induced cardiac syncope from epileptic attacks may lead to an increase in dosage and aggravation of syncope.
منابع مشابه
Pearls and oy-sters: ictal syncope in a patient with temporal lobe epilepsy.
PEARLS & OY-STERS: ICTAL SYNCOPE IN A PATIENT WITH TEMPORAL LOBE EPILEPSY Nitin K. Sethi, New York: Varade et al. reported ictal syncope in a patient with temporal lobe epilepsy (TLE). The MRI revealed a right temporal-occipital cavernous angioma and the seizure showed onset in the right posterior temporal electrode (T6) on EEG, all compatible with a diagnosis of symptomatic localization-relate...
متن کاملManagement of severe scorpion sting at a rural hospital.
aggravated by carbamazepine therapy for epilepsy. Postgrad Med J. 1986;62:497-8. 2. Tomson T, Kenneback G. Arrhythmia, heart rate variability, and antiepileptic drugs. Epilepsia. 1997; 38:S48-51. 3. Kasarskis EJ, Berger R, Nelson KR. Carbamazepineinduced cardiac dysfunction. Characterization of two distinct syndromes. Arch Intern Med. 1992;152:186-91. 4. Kennebäck G, Ericson M, Tomson T, Bergfe...
متن کاملSick sinus syndrome in childhood.
The clinical and electrocardiographic findings in five children with the sick sinus syndrome and an otherwise normal heart are described. There were three boys and two girls. Their age at onset of either bradycardia or symptoms ranged from 1 day to 7 years. In one patient, the youngest ever reported with this syndrome, bradycardia was noted before birth. Four children presented with neurologica...
متن کاملNeuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline
A 32-year-old female, with a history of secondarily-generalized convulsive epilepsy, mental retardation, and a psychiatric illness, developed neuroleptic malignant syndrome while receiving carbamazepine and amitriptyline concurrently. We hypothesize that the addition of amitriptyline to carbamazepine caused a decrease in the serum level of carbamazepine, resulting in NMS. We conclude that combi...
متن کاملAggravation of symptomatic occipital epilepsy of childhood by carbamazepine.
INTRODUCTION Carbamazepine can lead to aggravation of epileptic seizures in generalized epilepsies (primary or secondary) with clinical manifestations of absence (typical or atypical) and/or myoclonic seizures. However, some focal epilepsies can be also aggravated by the introduction of carbamazepine. CASE REPORT We presented a 10-year-old boy born after a complicated and prolonged delivery c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 62 728 شماره
صفحات -
تاریخ انتشار 1986